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Disintegrating Sphere

Transform Your Longevity & Functional Medicine Practice with PhysioAge

Track real-time physiological age and provide letter-grade lab insights to better engage patients, showcase treatment efficacy, and elevate your practice.

Practice better medicine with clear biomarker & age analytics

Demonstrate measurable results of your treatments

Enhance patient compliance and engagement

Measure Physiological Age

Compare patient's physiological ages against their chronological ages in up to 9 systems. See how lifestyle interventions or treatments are moving the needle in real time!

Why Providers Choose PhysioAge

Data-Driven Insights:

Quantify and track treatment efficacy over time

High-Tech PR Advantage:

Position your clinic as an innovative leader in personalized health

Patient Engagement:

Improved compliance through simple letter-grade feedback and interactive charts

Revenue Growth Opportunity:

Retain patients, offer premium services, and attract new referrals

Unlock Better Results and Practice Growth—Request Your Free Demo Now!

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  • Can PhysioAge integrate with my existing EMR?
    While we don’t offer full EMR integration at this time, you can easily upload lab results to our Virtual Assistant, who will enter the data on your behalf.
  • How can I market the availability of PhysioAge in my practice?
    PhysioAge subscribers are entitled to use any content from PhysioAge.com, including images, text, downloads and videos, on their own website. Use the same content in your email marketing campaigns.
  • How do I sign up?
    Signup form
  • Do I need equipment?
    No equipment is required unless you wish to collect measurements for the following biomarkers: CardioAge - CONNEQT Pulse PulmoAge - Any spirometer CutoAge - Cutometer
  • How often should I test my patients?
    Tracking physiological age over time provides a clear and detailed profile of the body’s individual aging process and helps direct interventions. For this reason, we recommend repeating most testing every 6 months.
  • What if I don’t like the software?
    Try the software for 60 days at no charge Cancel your subscription at any time for any reason
  • How do I get trained to use PhysioAge in my practice?
    We offer onboarding calls, video tutorials, and live support to ensure seamless adoption. A clinical success team will walk you through your first assessments and show you how to interpret reports and integrate the platform into your workflow. We also offer webinars and case reviews to keep you and your team up to date and confident.
  • How much does the software cost?
    Basic Analytics is available at a cost of $300/month. Premium Analytics is available at $500/month, including unlimited Virtual Assistant Data Entry. Professional Analytics is available at $800/month, including full customization capabilities. The Cardiex CONNEQT Pulse device is available for an additional $50/month upcharge.
  • What is PhysioAge and how does it work?
    PhysioAge is a biomarker-based platform that quantifies biological aging across multiple systems. It combines advanced diagnostics with proprietary algorithms to produce personalized aging metrics that guide evidence-based longevity care.
  • How long does it take to onboard my practice?
    Your site instance is available immediately upon enrollment. Lab interfaces can take 2-10 weeks. We support you with technical setup and available staff training so you’re confident from day one.
  • What equipment or labs are required to use PhysioAge assessments?
    Most assessments require commonly available labs (e.g., CBC, lipid panel, glucose, hs-CRP), along with optional tests like carotid IMT and pulmonary function. Many of our providers already have the necessary equipment or work with partner labs.
  • Are any biomarkers reimbursable by insurance companies?
    You may find success submitting the following tests for reimbursement: Spirometry CONNEQT Pulse CNS Vital Signs (neurologists only)
  • Is any type of commitment required?
    No commitment is required
  • Which panels should I choose when enrolling?
    During the enrollment process, you’ll have the opportunity to choose an unlimited number of default panels to appear whenever you create a new visit. See our complete list of panels here. Only choose the panels you wish to offer in your practice at first. You can easily add new panels in the future.
  • Which plan should I choose?
    To take advantage of Virtual Assistant Data Entry Service, we recommend all providers start with the PhysioAge Analytics Premium plan and upgrade at a later time if customization is required.
  • How does PhysioAge integrate with functional and longevity medicine protocols?
    PhysioAge is designed to complement root-cause and systems-based care. It helps prioritize interventions by showing which organ systems are aging fastest and measuring response to treatments, whether hormone therapy, detox, or lifestyle changes.
  • What specimen handling requirements apply to each blood biomarker?
    PhenoAge - none (automatically generated from routine blood tests) GlycanAge - Have kits shipped to your office or to patients directly. Your office or your patient will collect the bloodspot specimens and send them to the lab (US or UK) at ambient temperature. The results go directly to you. Click here to place your first order. TruAge - Click here to set up an account with Trudiagnostic and have kits shipped to your office. You’ll collect the specimens in your office and send them to the lab (US) at ambient temperature. The results go directly to you. ImmunoAge - Lavender-top tube mailed at room temperature within 48 hours to LA, California (no kit required). TelomerAge Repeat Diagnostics (recommended) - Lavender-top tube mailed at room temperature within 48 hours to Vancouver, Canada (no kit required). Lifelength - Special kit sent to partner labs in USA, Canada, Mexico, Colombia, Brazil, Japan, Indonesia, Dubai, Turkey and India.
  • What if my panel isn’t listed?
    We can work with you to develop a custom panel at an additional charge. To get a quote, send a sample report to support@physioage.com.
  • What about wearables like Oura?
    We don’t currently support integrations with wearable devices.
  • How do you help prevent data entry errors?
    If results entered are outside the normal reference range, the row will turn pink as a visual indicator of potential error. If results entered are not humanly possible, the row will turn red and display a message “Out of bounds”. Such results can’t be saved without being corrected.
  • What if my electronic interface isn’t listed?
    We can work with you and your lab to develop a custom interface at an additional charge.
  • What panels are available?
    See this list of available panels.
  • How do I enter data into the software?
    Data can be entered manually or automatically via electronic interface. Premium and Professional subscribers qualify for Virtual Assistant data entry by our RN.
  • What electronic interfaces are available?
    Quest Labcorp CNS Vital Signs Trudiagnostic GlycanAge UCLA Access Labs
  • How do I interpret a patient’s PhysioAge report?
    Our system provides several forms of interpretation: Physiological Ages: calculated using the most age-sensitive parameters, or simply passed through when previously calculated by labs such as Trudiagnostic or GlycanAge. Spectra interpret results along optimal ranges using an English description of each grade. Letter Grades (A-F): calculated based on a spectrum of optimal ranges, as determined by Dr. Raffaele in his clinical practice. Letter grades are calculated as follows: For individual parameters such as Free Testosterone For groupings such as Sex Hormones For Sections such as Hormone Health GPA: calculated as a straight average of underlying values and converted to a numerical score between 1 (poor) and 4 (excellent). In addition, Dr. Raffale has compiled a Biomarker Interpretation Guide for Providers to help with results interpretation.
  • What is Practice-wide analysis?
    Practice-wide analysis enables you to gain access to “data clouds” of every parameter across all patients by age and gender, as well as histograms of grades and values. Click on a dot in the scatter plot to see the visit behind that result. Download all results for slicing and dicing in Excel.
  • How are results reported?
    Health Analytics Portal is available from any device for patients and providers Our mobile app is available for iOS and Android phones. PDF reports are available for download: Comprehensive Patient Report Visit Summary Physician Report
  • What does each biomarker report look like?
    TruAge TruAge report TruHealth report GlycanAge GlycanAge report ImmunoAge UCLA Immune Function report TelomerAge Repeat Dx Telomere Length report NeuroAge CNS Vital Signs report CardioAge CONNEQT Pulse screens PulmoAge EasyOne Air report CutoAge Cutometer report
  • Can I use PhysioAge to track patient progress over time?
    Yes. Longitudinal tracking is a core feature. Repeat assessments show whether your interventions are slowing aging and improving physiological function, making it an ideal tool for lifestyle and supplement protocol evaluation.
  • How does PhysioAge integrate with functional and longevity medicine protocols?
    PhysioAge is designed to complement root-cause and systems-based care. It helps prioritize interventions by showing which organ systems are aging fastest and measuring response to treatments, whether hormone therapy, detox, or lifestyle changes.
  • Can I customize optimal ranges?
    Yes; Premium and Professional subscribers may customize optimal ranges.
  • Who decided on the optimal ranges used in your system?
    Dr. Raffaele chose our optimal ranges based on his 25+ years of longevity medicine practice and his review of the literature.
  • How does my patient view my recommendations?
    In their Health Portal under Treatment Plan (see above) In their Visit Summary report
  • How do I enter recommendations?
    Click on any result or category to display the drawer pictured below. In the Treatment Plan section you can make general recommendations not tied to a particular result or category.
  • What recommendation categories are available?
    General instructions Further testing Lifestyle Diet Exercise Supplements Hormone optimization Pharmaceuticals
  • How does PhysioAge make it easy to re-use previously entered recommendations?
    Previously-entered recommendations will appear in a drop-down as the provider types characters into the field. Sorting is based on frequency of use.
  • Can I add custom panels for tests I run in my practice?
    Yes, Professional subscribers may add custom panels for a small fee, depending on the number of unsupported tests requested.
  • Can I customize the fonts and colors of the portal to match my public website?
    Yes, Professional subscribers may customize the look and feel of the portal.
  • Can I customize GPA components?
    Yes, all subscribers may customize the components that make up the GPA.
  • Can I customize the PhysioAge report with my branding?
    Yes. You can add your practice name, logo, and contact information to the report for a white-labeled experience.
  • Can I add custom lab interfaces?
    Yes, Professional subscribers may add custom lab interfaces for an additional fee.
  • Can I customize optimal ranges?
    Yes; Premium and Professional subscribers may customize optimal ranges.
  • Can I delegate PhysioAge assessments to a nurse or technician?
    Yes. Most data collection (labs, imaging, vitals) can be performed by staff. The provider typically interprets and presents the final report during a consultation.
  • How can PhysioAge help generate revenue for my practice?
    PhysioAge can be packaged into concierge and longevity programs as a premium feature. It’s often used as a differentiator and upsell within annual membership models. Fee-for-service providers typically charge between $200 and $500 for an assessment, depending on the number of tests interpreted (including CNS Vitall Signs but not including individual testing fees such as GlycanAge, etc.)
  • What’s the average reimbursement model for services associated with PhysioAge?
    While PhysioAge itself is typically part of a cash-pay model, components like labs and vascular testing may be eligible for insurance reimbursement depending on your coding and payer agreements. You may find success submitting the following tests for reimbursement: Spirometry CONNEQT Pulse CNS Vital Signs (neurologists only)
  • How do other providers incorporate PhysioAge into their cash-pay or concierge models?
    Many bundle it into initial assessments, yearly re-evaluations, or longevity programs. It’s used to personalize care plans and justify ongoing membership fees.
  • Is physician training available?
    Physician training may be available from Dr. Raffaele for an additional charge (depending on availability). Dr. Raffaele may respond to your simple clinical questions by email at no charge. Response time varies.
  • I still have questions
    We have answers! Schedule a call with Jerry Fortunato, Co-founder.
  • Is PhysioAge HIPAA and GDPR compliant?
    Yes. Our platform is fully HIPAA and GDPR compliant and hosted in secure cloud environments with proper encryption and access controls.
  • What if I need support?
    The following technical support options are available to all clients: Phone support (Schedule a call) Email support (support@physioage.com) HELP section in PhysioAge Analytics: Account Setup Guide User Guide Biomarker Interpretations for Providers Biomarker Testing Manual Videos

Ready to See PhysioAge in Action?

Book your demo today.

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