A list curated by our chief medical officer, Joseph Raffaele MD
Published by Dr. Raffaele
A natural product telomerase activator as part of a health maintenance program: metabolic and cardiovascular response.
Rejuvenation Res October 16, 2013
A Natural Product Telomerase Activator Lengthens Telomeres in Humans: A Randomized, Double Blind, and Placebo Controlled Study.
Rejuvenation Res Dec 2016
Anti-aging medicine. Partners put evolutionary theory into practice. Interview by Alice V. Luddington.
Geriatrics August, 2000
Biomarkers of Aging: General considerations and composite indices
A method for identifying biomarkers of aging and constructing an index of biological age in humans.
J Gerontol A Biol Sci Med Sci Oct 2007
Reduction in allostatic load in older adults is associated with lower all-cause mortality risk: MacArthur studies of successful aging.
Psychosom Med May-Jun 2006
Disentangling the genetic determinants of human aging: biological age as an alternative to the use of survival measures.
J Gerontol A Biol Sci Med Sci. May 2005
Biomarkers of aging: from primitive organisms to humans.
J Gerontol A Biol Sci Med Sci. Jun 2004
Biological age--what is it and can it be measured?
Arch Gerontol Geriatr Mar-Apr 2003
Arterial System Aging
Arterial aging: pathophysiological principles.
Vascular Medicine November 2007
Arterial and Cardiac Aging: Major Shareholders in Cardiovascular Disease Enterprises: Part I: Aging Arteries: A "Set Up" for Vascular Disease. Circulation
Curculation January 21, 2003
Arterial and Cardiac Aging: Major Shareholders in Cardiovascular Disease Enterprises: Part III: Cellular and Molecular Clues to Heart and Arterial Aging.
Circulation January 21, 2003
Central Pressure More Strongly Relates to Vascular Disease and Outcome Than Does Brachial Pressure: The Strong Heart Study
Hypertension July 2007
Differential impact of blood pressure-lowering drugs on central aortic pressure and clinical outcomes: principal results of the Conduit Artery Function Evaluation (CAFE) study
Effects of GH replacement on endothelial function and large-artery stiffness in GH-deficient adults: a randomized, double-blind, placebo-controlled study.
Normal vascular aging: differential effects on wave reflection and aortic pulse wave velocity: the Anglo-Cardiff Collaborative Trial (ACCT).
Pulmonary System Aging
COPD as a disease of accelerated lung aging.
Chest Jan 2009
John Hutchinson's mysterious machine revisited
Chest May 2002
Reduced pulmonary function is associated with central arterial stiffness in men
Am J Respir Crit Care Med Dec 2001
Pulmonary Function Is a Long-term Predictor of Mortality in the General Population : 29-Year Follow-up of the Buffalo Health Study
Chest Sep 2000
Decline in lung function and mortality: the Busselton Health Study
Lung function, respiratory symptoms, and mortality: results from the Busselton Health Study
Spirometric Reference Values from a Sample of the General U.S. Population
Mortality associated with respiratory function and symptoms in advanced age. The Framingham Study
Application of Cutometer area parameters for the study of human skin fatigue
Skin Res Technology May 2005
Estrogens and the skin
Climacteric June 2005
Effects of aging and postmenopausal hypoestrogenism on skin elasticity and bone mineral density in Japanese women
Endocrine Journal April 2004
Effects of aging, menopause, and hormone replacement therapy on forearm skin elasticity in women
Journal of American Geriatrics Society June 2004
Skin biophysical properties of a population living in Valais, Switzerland
Skin Res. Technology November, 2003
Mechanisms of Photoaging and Chronological Skin Aging
Arch Dermatol Nov 2002
Hormone replacement therapy and the skin: beneficial effects: the case in favor of it
Acta Obstet Gynecol Scand April 2000
Ageing and rheological properties of facial skin in women
Treatment of skin aging with topical estrogens
International Journal of Dermatology September, 1996
Age-associated cognitive decline
Br Med Bull 2009
Insights into the ageing mind: a view from cognitive neuroscience
Memory and executive function in aging and AD: multiple factors that cause decline and reserve factors that compensate
Dehydroepiandrosterone (DHEA): a misunderstood adrenal hormone and spine-tingling neurosteroid?
Estrogen and cognition: a true relationship?
All in your mind.
Cognitive effects of short-term manipulation of serum sex steroids in healthy young men
Cellular and molecular mechanisms of estrogen regulation of memory function and neuroprotection against Alzheimer's disease: recent insights and remaining challenges
Insulin-like growth factor-I and cognitive function in healthy older men
Immune System Aging
CD28(-) T cells: their role in the age-associated decline of immune function
Biomarkers of human immunosenescence: impact of Cytomegalovirus infection
Cytomegalovirus-seropositivity has a profound influence on the magnitude of major lymphoid subsets within healthy individuals.
Mechanisms of immunosenescence. Immun Ageing
No Immune Risk Profile among individuals who reach 100 years of age: findings from the Swedish NONA immune longitudinal study
Telomerase induction in T cells: a cure for aging and disease?
CD8 T-cell immune phenotype of successful aging
Shortage of circulating naive CD8(+) T cells provides new insights on immunodeficiency in aging
Telomere Attrition and Aging
A Natural Product Telomerase Activator as Part of a Health Maintenance Program
Rejuvenation Res 2010
Telomere length is shorter in healthy offspring of subjects with coronary artery disease: support for the telomere hypothesis
Telomeres and aging
Physiol Rev April 2008
Leukocyte telomere length and cardiovascular disease in the cardiovascular health study
Am J Epidemiol 2007
Telomere length, risk of coronary heart disease, and statin treatment in the West of Scotland Primary Prevention Study: a nested case-control study
Lancet January 2007
Telomere length, stem cells and aging
Nat Chem Biol 2007
Telomeres and human somatic fitness
J Gerontol A Biol Sci Med Sci 2006