Skip to main content

Equip your practice to deliver next-generation physical exams

For Providers

Biomarkers of Aging

An unparalleled and focused array of extensively-tested biomarkers that have been shown to highly correlate with age.
  • Measures the suppleness of your arteries using pulse wave analysis
  • Assesses cardiovascular risk by measuring augmentation pressure

The gold standard in central blood pressure assessment, the SphygmoCor has been used in more clinical studies than any other device. Central blood pressure has been shown to be a superior predictor of cardiovascular events. In fact, the Mayo Clinic has adopted the Sphygmo-Cor as the standard hyper-tension screening device.

Functioning essentially like an non-invasive A-line, SphygmoCor CP takes a 10-second snapshot of the radial arterial pres-sure wave and derives the ascending aortic pressure wave, providing critical cardiovascular measurements including cen-tral blood pressure, aortic aug-mentation index, ejection duration and subendocardial viability ratio. Our algorithms calculate a CardioAge based on augmentation pressure, the most age-sensitive measurement generated.

  • Assesses the elasticity of the skin with the same instrument used in numerous clinical trials of OTC and pharmaceutical skin care products
  • Determines the propensity to develop wrinkles by measuring elasticity, firmness, and resistance to stress

The Cutometer MPA 580 is the gold standard in dermatology to measure elasticity and other biomechanical parameters of the skin. The device uses gentle suction to draw the skin into the aperture of the probe, where penetration depth is deter-mined by an optical measuring system. The resistance of the skin to be sucked up by negative pressure (firmness) and its ability to return into its original position (elasticity) are dis-played as curves. Our algorithms calculate a CutoAge based on the most age-sensitive parameters of these curves.

  • Measures forced expiratory volume (FEV1/FCV), which is highly correlated with age
  • Predicts all-cause mortality, not just mortality from pulmonary disease
EasyOne Air - Digital Spirometer

The EasyOne Air digital spirometer is a flexible, accurate and proven spirometry solution designed for healthcare providers large and small. Utilizing TrueFlow™ technology, this portable spirometer delivers reliable results without the need for calibration to ensure lifetime worry-free operation.

Thanks to the vivid color touch screen, it is easy to navigate, view real-time results and enter data. Easily connect to a PC for real-time patient incentives, data exchange and EMR connectivity.

Of the parameters measured by the EasyOne Air Spirometer, FEV1 is the most age-sensitive. Our algorithms calculate a PulmoAge based on FEVI corrected for race, age, sex and height.

  • Measures the most highly age-sensitive aspects of cognitive function using a computerized battery of tests
  • Functions as an effective screen for mild cognitive impairment and Alzheimer’s disease

CNS Vital Signs online neurocognitive assessment is a non-invasive clinical procedure to efficiently and objectively assess a broad spectrum of brain function performance or domains under challenge (cognition stress test) to enable the measuring of important clinical symptoms, behaviors, and comorbidities. Of all the parameters measured by CNS Vital Signs, the most age-sensitive are psychomotor speed and processing speed. Our algorithms calculate a NeuroAge using these two parameters.

  • Measures the health of the immune system using proprietary algorithms of standard immune subsets
  • Utilizes cutting-edge molecular markers for senescent and naïve T-cells
  • Measures the ends of the telomeres, the caps at the ends of your chromosomes that act as a molecular clock by shortening with every cell division
  • Telomere shortening is highly correlated in numerous studies with aging and many disease states

Built on Solid Science

Medical and statistical significance
Detail and precision are crucial differences that set PhysioAge apart from other health tests.

Our expert system is based on solid science – extensive clinical trials, scientific literature, and careful statistical analysis of primary data. Rather than using secondary clinical studies to calculate physiological age, we used our own in-depth primary research to measure up to 120 attributes in a database of 4,500 individuals. This study determined how biomarkers relate to each other, which enabled a greater degree of statistical accuracy and a deeper understanding of the aging process. With unique in-house measurements, PhysioAge® gives you complete, clear, and precise results.

Selected References


PhysioAge includes an online reporting system that includes a Dashboard, Report Cards, Recommendations, and Reports.
PhysioAge Dashboard
A dynamic interface for browsing all results including biomarkers, labs, questionnaires and any other tests you choose to include. Some providers use the dashboard during consultations to help patients visualize their results.
Report Cards
Our algorithms assign letter grades (A through F) for each result category as well as individual results, in an easy-to-understand format familiar to most patients.
Our software will collect your custom treatment recommendations and compile them in one place for maximum compliance. It's easy to create and select your most commonly-used recommendations.
PDF Reports
Generate several PDF reports of various lengths, from a 2-page digest to a 40-page report with full explanations of each test and what the results mean to you.


PhysioAge includes all of the support services you need to get up and running delivering high-quality next-generation physical exams.
  • Software & Lab Equipment Setup
  • Clinician and Technician Training
  • Unlimited patients and visits
  • Patient Materials and Marketing Support Learn More

Benefits of Becoming a PhysioAge Provider

  • Better data about your patients' health
    Gain access to research grade hardware, software, and bloodwork
  • More context about your patients' health
    Not just more data but a better understanding of how your patients compare to their peers and their past
  • Improved patient engagement
    PhysioAge produces results that are meaningful to your patients and that can highlight the impact of treatments
  • More efficient consultations
    Spend less time explaining results and more time focused on treatments
  • Increased revenues
    Grow your bottom line by offering a differentiated service that keeps your patients coming back year after year

PhysioAge ROI

PhysioAge is designed to fit into a wide variety of practice business models to grow your bottom line. Whereas some practices offer our assessment on a fee-for-service basis, our most successful clients build regular biomarker testing into their service offering.

Depending on the business model, most practices break even at 3 assessments per month. At 6 assessments per month, you can expect to pay back your initial investment within 18 months.

Regardless of how physioAge is packaged, it will help you attract more patients, generate more revenue from existing patients, and keep your patients coming back year after year.